Myocardial Infarction in a Patient Treated with Anti-Interleukin-12 Biological Agent for Chronic Plaque Psoriasis

نویسندگان

  • Giuseppe Stinco
  • Cinzia Buligan
  • Serena Bergamo
  • Olvino Morgante
  • Maria Antonietta Iacono
  • Pasquale Patrone
چکیده

Vol. 26 No. 1, 2014 137 Received January 3, 2013, Revised March 5, 2013, Accepted for publication March 27, 2013 Corresponding author: Giuseppe Stinco, Institute of Dermatology, University of Udine, Ospedale “San Michele” di Gemona piazza Rodolone 1, Gemona del Friuli (Udine) 33013, Italy. Tel: 39-0432-989378, Fax: 39-0432-989209, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. loricrin, and filaggrin in cultured sebocytes. In conclusion, cultured sebocytes showed little expression of keratinocyte differentiation markers. Weak physical barrier in the sebaceous gland may cause much better transfollicular drug delivery.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Emerging targeted therapies for plaque psoriasis – impact of ixekizumab

BACKGROUND Recent studies into the pathogenesis of psoriasis have identified the importance of interleukin 17 (IL-17) in disease activity and have thus provided a new target for biologic therapy. Ixekizumab, the most recent US Food and Drug Administration (FDA)-approved anti-IL-17 biologic agent, appears to be a promising medication for patients suffering from moderate-to-severe plaque psoriasi...

متن کامل

Cardiovascular risk factors in patients with psoriasis: A casecontrol study

Recent studies suggest that psoriasis may be an independent risk factor for the development of cardiovascular diseases. Myocardial infarction, pulmonary embolism, diabetes mellitus,hypertension, and dyslipidemia have been reported in patients with psoriasis Certain risk factors for cardiovascular diseases may be more prevalent among patients with psoriasis 3,4. The aim of this study was to defi...

متن کامل

Metabolic comorbidities and psoriasis.

Psoriasis is a chronic inflammatory, immune-mediated skin disease, which affects 2%-3% of the population worldwide. Chronic plaque psoriasis is frequently associated with metabolic diseases including diabetes, obesity, dyslipidemia, metabolic syndrome and nonalcoholic fatty liver disease. Although the causal relationship between metabolic comorbidities and psoriasis has not yet been completely ...

متن کامل

A Randomized Comparative Study Between Three Times And Five Times Weekly Phototherapy With NBUVB For Treating Chronic Plaque Type Psoriasis

Background: Psoriasis is a chronic inflammatory skin disease that is estimated to affect 0.6% to 4.8% of the general population. The optimum number of NB-UVB phototherapy sessions is yet to be determined. The aim of this study was to compare therapeutic effects of NB-UVB in treating chronic plaque type psoriasis three times weekly vs. five times weekly. Materials and Methods: This study was des...

متن کامل

Role of Fructose as a Potent Antiarrhythmic and Anti-infarct agent in Isolated Rat Heart

In the current study, effects of acute short term administration of fructose on cardiac arrhythmias and myocardial infarction size following ischemia/reperfusion were investigated in isolated rat heart. The hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusion. In the control group, the hearts were perfused by normal drug free Krebs-Henseleit (K/H) solution t...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 26  شماره 

صفحات  -

تاریخ انتشار 2014